Svalová dystrofie

26.4.2012 , Vladislava Králová

svalova-dystrofie.jpg - kopie
svalova-dystrofie.jpg - kopie
Svalová dystrofie se projevuje postupující svalovou bolestí a zmenšováním svalové hmoty. Svalová dystrofie vzniká nesprávnou tvorbou proteinu dystrofinu, který je pro správnou funkci svalu nezbytný. Svalová dystrofie je geneticky podmíněné onemocnění, které má nejčastěji dvě formy – Duchennoevu svalovou dystrofii a Beckerovu svalovou dystrofii.

Svalová dystrofie

Jako svalová dystrofie je označována celá skupina onemocnění, která se projevuje postupující svalovou slabostí a zmenšením svalové hmoty. Tato onemocnění jsou geneticky podmíněná. Dnes se jednotlivé typy svalových dystrofií určují na základě genetiky, kdy je diagnostikována specifická mutace. Dvě nejčastější jednotky jsou Duchennoeova svalová dystrofie a Beckerova svalová dystrofie. U obou těchto jednotek je podstata onemocnění vázaná na dystrofin. Jedná se o protein přítomný v cytoskeletu svalové buňky, který váže další proteiny a podílí se na určování koncentrace vápníkových iontů ve svalové buňce. Gen pro tento protein je jeden z největších známých genů a nachází se na X-chromozomu.

Duchennoeova svalová dystofie

Duchennoeova svalová dystofie je nejčastějším typem svalové dystrofie, představuje však i formu nejzávažnější. Vyskytuje se s četností 1:3500 narozených chlapců. Ženy jsou pouze přenašečky, které nemají žádné nebo jen minimální potíže. V důsledku mutace genu pro dystrofin dochází k úplnému chybění tohoto proteinu. Dodnes se jedná o smrtelné onemocnění, které neumíme léčit. Chlapci se rodí zdraví, někdy lze sledovat opožděný psychomotorický vývoj. Příznaky se vyvinou nejpozději mezi 3.–5. rokem. Dochází k postupnému nárůstu svalové slabosti, která postihuje nejdříve dolní končetiny a pánevní svaly, později jsou postiženy svaly horních končetin, krku a dechové svaly. Mezi první příznaky řadíme kolébavou chůzi, nemocní se nemohou zvednout ze dřepu bez pomoci horních končetin, velké problémy jim činí chůze do schodů. Zpravidla kolem desátého roku nejsou již schopni chůze a jsou upoutáni na invalidní vozík. Dochází ke zkracování svalových skupin a jejich vazivové přeměně, která vede k vadnému držení těla. Páteř je postižena skoliózou. Jsou častější záněty dýchacích cest. Postižena je i srdeční svalovina. Srdeční oddíly jsou výrazně rozšířené. Takto postižené srdce je náchylnější ke vzniku sraženin a jejich následných vmetení do krevního oběhu a ke vzniku poruch srdečního rytmu. Ke smrti dochází zpravidla kolem třicátého roku. Příčinou je buď postižení dýchacích svalů, které vede k dechovému selhání, nebo poruchy rytmu, které vedou k srdečnímu selhání.

Beckerova svalová dystrofie

Beckerova svalová dystrofie by se dala popsat jako mírnější forma Duchennoeovy formy. Dystrofin je zde tvořený, ale mutace vede k jeho pozměnění. Projevy mohou být různě závažné. Nejmírnější forma je představována svalovými bolestmi a křečemi. V nejtěžší podobě se průběh od Duchennoeovy formy příliš neliší. Nejčastěji ale dochází k symetrickému postižení svaloviny končetin. Objem svaloviny je snížen, vyskytuje se svalová slabost. Projevy se vyskytují nejdříve v pěti letech, nejčastěji pak kolem dvanácti let.

Svalová dystrofie a její léčba

Léčba těchto chorob nemůže být zaměřena proti příčině, léčíme pouze příznaky. Pro zpomalení projevů nemoci jsou podávány léky ze skupiny imunosupresiv. Jelikož mají tyto léky řadu nežádoucích účinků, je nutné zvážit, jestli je jejich přínos vyšší než škody. Důležitá je důsledná rehabilitace jako prevence rozvoje zkrácení svalů. Používají se také pomůcky pro podporu chůze a ortézy. V pokročilejších fázích onemocnění je používána neinvazivní podpora dýchání, zpočátku pouze v noci. Nemocný pak spí s dechovou maskou, která je propojena s dýchacím přístrojem. Lékař musí vždy pátrat po známkách zánětu dýchacích cest a především je útočně léčit. Prevence tohoto onemocnění není možná. Důležité ze strany pacienta je dodržovat rehabilitační cvičení a předcházet onemocněním dýchacích cest.

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Craigtaili: Приобрести можно на веб-сайте http://mang.bestseller-super.ru

<h1>Каким образом возможно вкусно и легко сбросить вес - уникальный сироп мангустина!</h1>
<p>В связи с реалиями жизни, когда из-за интенсивной работы не остается свободного времени подумать о себе, очень остро в обществе стоит вопрос лишнего веса. Люди, а особенно девушки, стремящиеся похудеть, пьют целый комплекс порошков и таблеток, которые в теории могут помочь. Однако, на практике это не подтверждается. Ничего удивительного в этом нет – каждая девушка неповторима, обобщающие приемы избавления от излишнего веса не работают.</p>
<p>Но принципиально новый мангустин для похудения качественно выделяется от других препаратов. И сейчас вы сможете узнать по каким причинам.</p>
<h2>Пополнеть не страшно, страшно жить с этим!</h2>
<p>Лишний вес – это проблема, которая отравляет жизнь подавляющей массы женщин. Исследования демонстрируют, что больше 90% полных людей очень мучаются от низкой самооценки и недовольны своим телом, что сильно сказывается на их личной жизни.</p>
<p>Это не голословные заявления: лишний вес появляется не просто так, а с большими психологическими и физическими проблемами:</p><ul>
<li>Рискованное последствие ожирения - диабет. Заболевание опасно, в первую очередь, тем, что часто становится предвестником инсульта.</li>
<li>Девушки с избыточным весом подвергаются перепадам давления и головным болям, что серьезно усложняет жизнь и сможет пошатнуть нервную систему. Особенно это ощущается знойным летом.</li>
<li>Неприятности с сердцем, которые ведут к сердечным катастрофам.</li>
<li>За избыточным весом следуют гормональные изменения. Они пугают тем, что смогут помешать осуществить мечту большинства девушек - завести детей.</li>
<li>Часто полнота может привести к варикозу и остеохондрозу.</li>
<li>И, безусловно, излишний вес влияет на дыхание.</li></ul>
<p>Избыточный вес визуально добавляет человеку 7-10 лет, это делает его гораздо менее привлекательным.</p>
<h2>Уникальное средство для успешного похудения</h2>
<p>Предпосылки полноты бывают разными: гормональные сбои, малоактивный образ жизни, медленный обмен веществ, остаточные последствия родов, нежная любовь к сладкому, невозможность правильно покушать из-за графика работы. Также, как и многочисленны характеристики худеющих – начав от роста и возраста, заканчивая количеством часов сна. Все это редко зависит от воли самого человека – нельзя определить установки своего организма. Но разбираться с ожирением в итоге приходится.</p>
<p>Практически все известные средства для похудения обобщают эти показатели, стараясь создать препарат, который подойдет всем. Мы идем по другому пути.</p>
<p>Мангустин, сироп для эффективного похудения – это препарат, который создается индивидуально под каждого потребителя с учетом свойств организма. Четыре года мы выполняли исследования и еще два – создавали специальную формулу, чтобы полученный эффект оказался удачным.</p>
<p>Стоит рассказать, по какой причине наше средство называется «Мангустин» – мангуст, также как и манго абсолютно ничего общего не имеют с ним. Дело в том, что главным элементом является мангустин – это тропический фрукт из Таиланда. Он прославился очень низкой калорийностью, а также набором витаминов и микроэлементов. Но настоящий мангустин купить в магазине и похудеть с его помощью не удастся. Поскольку перевезти плод в страны СНГ — значит растерять половину его пользы. Поэтому мы извлекаем все активные вещества из фрукта, а затем превращаем их в сироп, помогающий избавиться от лишнего веса. Помимо этого, в препарате применяются еще около 30 веществ натурального происхождения, ведь мы ищем самые результативные продукты.</p>
<p>Как Вы могли заметить, все самые современные технологии, которые вобрал в себя Мангустин – порошок для похудения уже остались в прошлом, также, как и таблетки. Мы постоянно беспокоимся о комфорте в процессе приема нашего продукта. Поэтому мы представляем сироп, который просто растворяется в воде и выпивается.</p>
<p>Результативность средства подтверждена практически. В случае если вы заинтересуетесь откликами на Мангустин, отзыв за отзывом от довольных покупателей убедят Вас сделать приобретение. Таким образом, и мужчинам, и женщинам, с разным набором особенностей и характеристик прекрасно подойдет Мангустин – реальные отзывы от людей, которые попробовали результат продукции на деле, Вы разыщете на сайтах, которые посвящены похудению.</p>
<h2>Где сейчас возможно купить данный продукт?</h2>
<p>Обращаем внимание на факт того, что купить Мангустин в аптеке или в первом попавшемся интернет-магазине невозможно. Заказать качественную продукцию имеется возможность лишь у нас на сайте, несмотря на все хитрости бесчисленных мошенников.</p>
<p>Если Вы хотите худеть результативно и вкусно, покупайте Мангустин – цена на такое сокровище приятно удивит, а город проживания не является особой проблемой. Поскольку мы осуществляем доставку по России, странам СНГ и по всей Европе.</p>


Приобрести можно на веб-сайте http://mang.bestseller-super.ru

13. listopadu 2018 18:31

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13. listopadu 2018 17:44

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