Lichen planus

8.4.2012 , Jiří Dyntr

lichen-planus.jpg - kopie
lichen-planus.jpg - kopie
Lichen planus je kožní onemocnění dosud neobjasněného původu, vyskytující se souměrně na různých částech těla. Lichen planus je charakteristický červenohnědými lesklými skvrnami nepravidelného tvaru. Ačkoliv se nejedná o nijak nebezpečné onemocnění, některé pacienty může provázet celý život, jelikož zatím neexistuje žádný konkrétní lék, který by dokázal lichen planus úplně vyléčit.

Lichen planus

Lichen planus je poměrně obvyklé onemocnění kůže, jehož příčina není dosud přesně známá. Odborníkům se však podařilo zjistit, že v jeho průběhu probíhají obdobné děje, jako když imunitní systém příjemce odmítá transplantovaný orgán od dárce. Tedy že jde o autoimunitní reakci organismu, kdy vytváří látky proti vlastním buňkám těla, protože je pokládá za buňky cizí. Lichen planus se může vyskytovat v mnoha různých formách a jeho projevy jsou často velmi různorodé. Rozlišení od dalších, podobně se projevujících chorob kůže je proto poměrně obtížné.

Příčiny vzniku lichen planus

Příčina vzniku onemocnění zvaného lichen planus není dosud přesně známá. Jisté však je jedno a to, že toto onemocnění není nijak nakažlivé a není způsobeno žádným mikroorganismem. Byl však vypozorován jeho zvýšený výskyt při různých jiných onemocněních nebo při používání některých léčiv. Častěji se lichen planus objevuje jako součást alergické reakce při nesnášenlivosti některých léků. Mezi taková léčiva patří například léky na vysoký krevní tlak nebo na některé srdeční a cévní choroby. Dále je lichen planus považován za jednu z komplikací onemocnění jater, například při virové hepatitidě typu C. Lichen planus může též vzniknout jako doprovodný příznak při transplantaci, když tělo odmítá nevhodně zvolený transplantovaný orgán. V tomto případě dochází tedy k autoimunitní reakci.

Příznaky lichen planus

Lichen planus vytváří na kůži červenohnědé lesklé skvrny, které mají nepravidelný tvar. Tyto skvrny jsou obvykle lokalizovány souměrně na obou polovinách těla a typická je pro ně tendence ke splývání do větších výraznějších celků. Nejčastěji se kožní změny lichenu vyskytují na dlaňových stranách zápěstí, v křížové krajině a na nártech, kde také po jejich zhojení přetrvávají typická šedohnědá ložiska. Kromě klasických projevů může lichen planus vytvářet celou řadu dalších kožních změn a podle toho se dělí do mnoha skupin. V některých případech tak lichen planus postihuje především kůži trupu, genitálu nebo plosek nohou a dlaní. Jindy ale dochází také k poškození sliznice dutiny ústní a jejího okolí nebo také sliznici konečníku. Výjimkou není ani deformace nebo úplná ztráta nehtů či tvorba bolestivých prasklin na kůži s následným výrazným jizvením. Při mikroskopickém vyšetření kůže napadené touto chorobou, je dobře zřetelné výrazné přemnožení kožních buněk a také přítomnost vyššího počtu bílých krvinek.

Lichen planus a jeho komplikace

Po zlepšení až vymizení kožních projevů lichen planus, mohou na kůži zůstat tmavé skvrny. Ty jsou hnědě či šedě zbarvené. Nepůsobí žádné zdravotní problémy, spíše obtíže psychického rázu. Komplikace, kterými jsou kožní projevy, však ve většině případů samy zmizí. Pokud ne, lze tyto příznaky alespoň částečně zmírnit používáním speciálních hojivých mastí.Ve vzácných případech, kdy přetrvávají v dutině ústní vředy, může dojít až ke zvýšení rizika pro vznik rakoviny.

Léčba lichen planus

Účinná léčba onemocnění lichen planus, která by působila cíleně přímo proti jemu, v současné době bohužel neexistuje. Přesto se pomocí některých protizánětlivých přípravků daří projevy onemocnění tlumit a někdy dokonce dosáhnout tzv. spícího stavu, ve kterém onemocnění setrvává ve stejném stádiu určitou dobu a dále se nezhoršuje. Bez léčby je průběh onemocnění těžce odhadnutelný. V některých případech zcela odezní a už se znovu neobjeví, jindy se v různě dlouhých intervalech navrací v průběhu celého života pacienta. Obvykle přetrvává i několik let bez větších následků, ale může také způsobit rozsáhlé zjizvení sliznic i kůže, ztrátu vlasů a deformace nehtů, což pacientovi působí velké nepříjemnosti i po psychické stránce.

Prevence lichen planus

Prevence lichen planus je velmi obtížná a vzhledem k neznámým vyvolávajícím příčinám i špatně proveditelná. Prevence tohoto onemocnění zahrnuje zejména prevenci vzniku lichenoidních skvrn. Snažíme se proto nevysazovat předepsané léky, či naopak neužívat zbytečně léky, které mohou tyto kožní problémy způsobovat. V případě orální formy je vhodné léčit onemocnění ve spolupráci s vaším zubařem.

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8. září 2020 22:52

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The every day Beast

'I had become Wrong': Comey Admits to Fox News ended up being 'Significant Errors' in FISA ProcessFormer FBI Director James Comey admitted he was "inadequate, Noting on Fox News Sunday that the recently releasedJustice department inspector general reporton the Russia probe launch did find "key errors" In the FISA warrant purposes related to a former Trump campaign aide. following release of IG Michael Horowitz report on Monday, Comey is doing a bit of a victory lap, Pointing to the inspector general finding there was no political bias and the FBI had acceptable evidence and predicant to launch the Russia probe. Horowitz, around the other hand,Told congress last weekthat his report didn "Vindicate anybody" for this investigation.

earlier Kentucky Gov. Matt Bevin defends questionable pardons, Blames outrage on opportunism /react words and phrases >A defiant Matt Bevin says he would welcome a federal lookup into thecontroversial last minute pardons and commutationshe issued before leaving the governor office last week, Adding he is knowing beyond a doubt that somehe pardoned of crimes, Includingbrutal kill, Rape and child batter, Are blameless. "This can be very cathartic, Bevin shared The Louisville (Ky.) Courier daybook, Partof north america TODAY Network. Bevin even suggested that some of the county prosecutors who are the fiercestcritics of his pardons may end up as the onesinvestigated and prosecuted if federal researchers get involved.

CBS current information

Barr taps top prosecutor for key Justice Department roleAttorney General William Barr has elevated a former top federal district attorney in Brooklyn to help oversee day to day operations at the Justice Department as the No. 2 genuine in the deputy attorney general office, Senior unit officials said Monday. Attorney Office in the Eastern District of idaho. Barr recognized DuCharme for his "Superb common sense and steady hand, screaming him "One of the most seasoned and collegial attorneys" At the area.11 striking photos from 2019 show the US military in action over the worldAir National Guard Staff Sgt. Jon Alderman DoD pick Three F/A 18E Super Hornets allocated to the Knighthawks of Strike Fighter Squadron (VFA) 136 from Naval Air network (NAS) Lemoore flown fly in formation over the Sea Test Range in the pacific ocean on March 7, 2019 after filling in a training mission. Navy video / photo by Lt. Cmdr. Darin RussellMarines use a fire hose to extinguish a fuel fire during live burn teaching at Marine Corps Air Station Futenma in Okinawa, okazaki, japan, january. 25, 2019. The us and human rights groups estimate that between 1 million and 2 million people, as a rule ethnic Uighur Muslims, Have been detained in harsh diseases in Xinjiang as part of what Beijing calls an anti terrorism campaign. China has consistently denied any mistreatment of Uighurs.

18. srpna 2020 6:38

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5. srpna 2020 13:41

JustinTinue: adult dating Tips for locating passion in just 50

into 2017, had been 110.6 million single within. in the mean time, all the way through 1960, 72% of american adults got attached.for the, this isn essentially a very bad thing. numerous personals enjoyment from their whole liberation did not take long actually have been important the being single is ideal for your.after all, Single us americans may be unnecessarily pitied by means of countless as is also making short relationships, Getting healthy quite a few cases bettering your energy that flexibility.nonetheless, situation ones 50s and sensible be aware of what you are and what you dream about ranging from anyone, it's time to just go and come across an associate.so long as you discover want down the road then you definately not the only one. please read on for free dating online tips for finding are attracted to afterward 50.1. register with romance AppsThis is the first and most obvious call for locating a new date. ought to scientifically intoxicated, talk with fixing up nicely colleague kids.they definitely be ready to assist you just for this out of the ordinary business, it doesn't matter what a irritable teen may perhaps be.to get really good corresponds on the subject of seeing apps, you choose excellent photograph because of by hand. remain away from crowd or even a child photographs.one we recommend going out with applications to contemplate blossoms a partner is regarded as OurTime. because there are regarding romance applications provide, use trying out one by one.regardless of how, even though venturing out on days, certainly carry on trustworthy. relay a buddy that you about and be sure you stay in a general situate.2. unite workout program ClassesMost u. s citizens typically doing not getting your homework (throughout reality, most effective 23% men and women begin doing plenty of employ weekly!)take a look at hurt two birds through one flagstone to locate a coming exercise curriculums to reach up coming true love?yoga is a preferred choice and is exhilarating for making improvements to both your individual mental and physical well-being.not only will you be getting in shape, which motivates appeal to newlyweds, But you may also be achieving lots of new visitors at the same time.much better, components-not just of finding those is also much less frightening compared with what taking place sightless times if you will getting back into the dating world!3. get a new HobbyNot a physical fitness lady quite possibly put on want in order to meet an accomplice which usually delights in exercise? 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4. srpna 2020 10:47

JoshuaRaF: 13 online dating sites Tips for Women

After 15 years of taking photos of people to use for their Online dating profiles, They still ask me the same exact irritating questions before the photo shoot begins. Some of the most widespread requests are as follows: 1) Can you develop me look thin? 2) Can you get me look 20 years younger? 3) Can you airbrush all of my wrinkle treatment? 4) would you add hair to my head? 5) Can you make me appear to be a model? provided, needs,reasons <a href=https://ukrainianwomenonlinedating.blogspot.com/2019/06/how-do-you-know-about-ukrainian-girls.html>woman in russian</a> reasons for getting your picture taken is so that people will recognize you when they meet you in person. If you chat with someone Online for a period and eventually agree to meet, How is it supposed to work out when your profile pictures look not a single thing like you? Based on my own experiences with dating foreign girls, As <a href=https://ukrainianwomen.home.blog/2019/06/11/how-to-date-ukrainian-women-in-kiev%ef%bc%9f/>hot ukrainian girls</a> well as my experience with photographing people for their Online dating profiles, Here are 13 tips that I has shared with you regarding your Online dating profile. (Although these tips are mainly for single women from a single man s mind-set, Men often will glean a few things from them, together with.) 1) Add a current picture of you to ultimately your profile. By up-to-date, I mean an image that was taken today. If you can t afford to have pro pictures taken, Even a selfie will suffice if the lighting is decent. Just make sure that you take head shots as well as full length photos with a selfie stick or just hand your phone to a friend and ask him/her to take a few quick pictures of you. 2) Never post images of a picture. The hair and wardrobe from 1979, and also the flash reflecting off of the print, Make it painfully obvious that your picture was taken several years ago and that you don t like any of your current pictures. 3) Never use a group photo as your primary profile picture. How is your prospective future soulmate supposed to work out which person you are? Avoiding using lots of group photo files, ordinarily, Is wise. 4) Take mins to answer the basic questions in your profile. I generally ignore or block women who write me if they haven t bothered to even fill out the standard information in their profiles. I don t have time to ask each one of them a lot of questions just to uncover if we have anything in common. things should already be addressed when I read their profiles, as in marital status, using cigarettes habits, consume habits, connected with pets at home, And number of children at home. 5) Never post a picture of yourself that has been digitally altered. These ameliorations are usually very obvious. at the same time, When you meet someone in person and see your face sees the real you, Those airbrushed wrinkles and kilos are going to stand out even more. 6) Don t lie in your shape. if you are a chain smoker, as an example, Do not examine the non smoker box in your profile. accept is as true or not, I ve actually seen quite a few profiles of women without a penny but pictures of them smoking while claiming to be non smokers. It s preposterous. If a woman has no problem lying about something as noticeable as smoking, It makes me wonder what other things she has lied about and continues lying about. It also makes me wonder why she is so at ease with lying, as a rule. 7) Choose a username that says something both intriguing and true about you. for example, I ve run across women s profiles with usernames like SmilesAlways721 or AlwaysSmiling823 and all their pictures show them with big frowns on their faces. How can anyone drive them seriously? 8) Avoid posting multiple international dating profiles on the same site. It may sound preposterous but I have actually seen one woman post about a dozen profiles on the same site with slightly different usernames but with just one pictures. It makes her look tremendously desperate. 9) remain aerials. If all of a woman s visuals, principally tight selfie head shots, Are removed from way above her head, And she's got no full length shots, It seems obvious to me that she is attempting hide her obesity. 10) Avoid hidden. I have seen so many women hiding their bodies behind trees, office chairs, dogs, and other people in their pictures. the actual I see it, If a woman is very overweight, She inevitably will be honest and open about it in her profile. With all of the millions of single individuals, I would think that at least a few of them might be okay with, Or even drawn to, Big wives. I don t see how searching deceive people, still, Could ever possibly exercise session. 11) Avoid posting pictures of issues that aren t you, specially in your main profile picture. Too many women make the mistake of making their house, truck, dog, Or even several other random person their main profile picture. With untold numbers of other Online dating profiles to go through, Who has time to sift through pictures of dogs, auto's, produce, dwellings, And other random things to find the one picture of the person who wrote the profile? 12) Avoid posting pictures of yourself that taken in 1986. This relates to the first tip that I mentioned. even though it seems outlandish, I ve actually run across the sort of thing quite a few times. One sweetheart, for example, Posted pictures of herself that were taken many years earlier in this article. After chatting with her Online for several months and then on the phone for several more weeks, We agreed to meet for a casual pot of coffee somewhere but I was unable to recognize her when she showed up. She looked hardly anything like her picture. Her long a time, Curly black hair was now very briefly, straightaway, And platinum eagle blonde, She had bought an extra 100 pounds or so, and she had aged about a dozen years. She walked even me, nonetheless, And declared herself. plainly, She recognized me because I actually seemed like my picture. I left and never talked to her again. The horrible experience was extremely frustrating, galling, And a total waste of my time. 13) ensure you get your address right. Too so often, I run across women who claim to exist in Houston, TX but after chatting with them I find out that they live in some city lots of money of miles away. unquestionably, I block them after I look for the lie. if you in Houston, Then put that in your report. if you reside in Austin, still, Put that in your link. in that possition, Nobody has their time abused. On many internet dating, You can actually enter your exact zip code so that people who live nearby is often more inclined contact you. I hope these tips help you with your uniform dating experience.

4. srpna 2020 9:22

PrestonGiG: stiletto heel shoes service offered romance

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