Zvýšená funkce štítné žlázy

10.7.2012 , Zuzana Boučková

zvysena-funkce-stitne-zlazy.jpg - kopie
zvysena-funkce-stitne-zlazy.jpg - kopie
Zvýšená funkce štítné žlázy se projevuje zrychlením metabolismu celém organismu. Zvýšená funkce štítné žlázy může být primárně způsobena problémem přímo ve žláze či sekundárně onemocněním hypofýzy. Zvýšená funkce štítné žlázy se projevuje urychleným metabolismem, který vede k vyčerpání, únavě, průjmu či hubnutí. Dalším projevem bývá zvětšení žlázy a vypoulené oči.

Zvýšená funkce štítné žlázy

Zvýšená funkce štítné žlázy, odborně hypertyreóza, je stav, kdy žláza produkuje vyšší množství hormonů. Hypertyreóza je poměrně časté onemocnění, které během života postihne zhruba 1 % populace. Vzniká na podkladě řady různých chorob, jež mohou být nádorové i nenádorové povahy a mít více či méně závažné následky.

Štítná žláza

Štítná žláza je orgán uložený na přední straně krku patřící do endokrinního systému, který vyšetřuje a léčí endokrinolog. Endokrinní orgány jsou tvořeny žlázami, které produkují hormony neboli látky, pomocí nichž komunikují jednotlivé orgány s jinými. Zjednodušeně řečeno, pomocí hormonů se dozvídají jednotlivé části lidského těla, co mají dělat. Štítná žláza tvoří trijódtyronin (T3) a tyroxin (T4), které upravují spalování tuků, hospodaření s kyslíkem a zvyšují tvorbu bílkovin. Dále kalcitonin, který udržuje stálou hladinu vápníku jeho přesunem z krve do kostí, čímž například působí proti osteoporóze. To však platí pouze u normální hladiny kalcitoninu.

Příznaky zvýšené funkce štítné žlázy

Zvýšená funkce štítné žlázy má charakteristické příznaky, které jsou úměrné funkci hormonů. Pokud dojde ke zvýšené tvorbě trijódtyroninu a tyroxinu, které zodpovídají za urychlení metabolických procesů, budou procesy probíhat ještě rychleji. Tuky se rychleji odbourávají, což se může projevit hubnutím (5 %), tvoří se více bílkovin a zároveň se zvyšuje tělesná teplota. Mezi typické příznaky patří hubnutí, zvýšené pocení, snadná unavitelnost, neklid, úzkost, průjmy, u žen i poruchy menstruačního cyklu. Dále je u zvýšené funkce štítné žlázy zrychlená srdeční frekvence a může docházet ke vzniku srdečních arytmií. Množství příznaků a komplikací této choroby pochopitelně závisí na délce jejího trvání a působení zvýšeného množství hormonů (T3,T4) na tělesné tkáně.

Vznik zvýšené funkce štítné žlázy

Příčiny vzniku zvýšené funkce štítné žlázy se dělí na primární, kdy je chorobným procesem postižena přímo štítná žláza, a sekundární při onemocnění hypofýzy, která řídí uvolňování hormonů štítné žlázy.

Primární příčiny

Primární příčiny zvýšené funkce štítné žlázy jsou daleko častější než sekundární a jejich hlavním zástupcem je Gravesova-Basedovova choroba. Ta patří mezi autoimunitní onemocnění, která se vyznačují tvorbou protilátek proti buňkám vlastního těla. Imunitní systém doslova bojuje proti vlastním orgánům. A právě tyto protilátky narušují tvorbu T3 a T4, což vede k jejich zvýšenému vylučování do krve. Touto nemocí jsou nejvíce postiženy ženy mezi 30. a 60. rokem života. Kromě urychleného metabolismu lze na těchto nemocných pozorovat obvykle strumu neboli zvětšení štítné žlázy v přední části krku a „vypoulené" oči, tzv. exoftalmus. Druhou nejčastější příčinou zvýšené funkce štítné žlázy je adenom, což je nezhoubný nádor. Další příčiny jsou méně časté, jde především o záněty štítné žlázy, které se mohou obzvláště zpočátku projevovat hypertyreózou.

Sekundární příčiny

Sekundární příčiny zvýšené funkce štítné žlázy jsou poměrně vzácné a spočívají v poruše hypofýzy. Hypofýza je orgán uložený v mozku, který řídí tvorbu hormonů štítné žlázy. Jakmile dojde v řídícím centru k chybě, nejčastěji z důvodu nádoru, začne tento orgán produkovat více látek, které přímo zvyšují aktivitu štítné žlázy.

Diagnostika zvýšené funkce štítné žlázy

Při podezření na zvýšenou funkci štítné žlázy provádíme laboratorní vyšetření krve, které prokáže zvýšené hladiny hormonů. Nezbytné je odhalit příčinu onemocnění. Gaves-Basedowova nemoc se projeví v krvi. Adenom štítné žlázy odhalíme nejlépe pomocí ultrazvuku, který nám upřesní lokalizaci nádoru, velikost štítné žlázy a umožní zhodnotit okolní struktury, především lymfatické uzliny, které bývají u nádorových onemocnění zvětšeny. Ultrazvukové vyšetření je zcela nebolestivá metoda, která pomocí zvuku procházejícího přes tkáně zobrazuje struktury pod povrchem kůže.

Léčba zvýšené funkce štítné žlázy

Při léčbě zvýšené funkce štítné žlázy vycházíme z příčiny onemocnění, která je mnohdy rozlišná původem i léčbou. Základními užívanými léky jsou tzv. tyreostatika, která snižují tvorbu hormonů štítné žlázy. Tyreostatika používáme k zahájení léčby a normalizování stavu pacienta. Výsledky léčby postupně sledujeme a upravujeme jejich dávku. Nevýhodou tyreostatik jsou časté vedlejší účinky způsobující zčervenání obličeje a svědění kůže. Další možností je léčba radiojódem, která je založena na schopnosti štítné žlázy vychytávat jód, který je nezbytný pro tvorbu hormonů a její správnou funkci. Pokud však vychytává žláza radioaktivní jód, dochází k jejímu rozpadu. Tuto léčbu používáme obzvláště u nemocných s vysokým rizikem chirurgického zákroku. Chirurgická léčba (tyreoidektomie) je nejčastějším definitivním řešením zvýšené funkce štítné žlázy. U nemocných s Graves-Basedowovou chorobou volíme úplné odstranění štítné žlázy. V případě adenomu indikujeme částečné odstranění žlázy, přesněji řečeno postiženého laloku.

Prognóza

Prognóza léčby zvýšené funkce štítné žlázy je při správné diagnóze příznivá. Do velké míry však záleží na původu onemocnění. Graves-Basedowova choroba se často a opakovaně vrací, než dosáhneme normálního stavu, proto volíme chirurgické odstranění. Neléčená hypotyreóza je život ohrožujícím onemocněním zejména u rizikových pacientů.

Diskuze:

JoshuaRaF: Maranatha Siblings have combined for 14 Wins

It not being the least bit hyperbolic to say that Dawson Netz and his younger sister Devyn make up ca has been most dominant brother sister duo when it comes to pitchers at the high school level.

As extraordinary as their skills and statistics would bear out, Dawson and Devyn are much more than just pitchers on the Maranatha High School baseball and softball teams, Respectively.

Their focus and priorities in life, that include attempts to stay as close to perfect academically as possible, Doing what best for their bodies and representing their parents and family in the brightest light possible are as much who they really are as the gaudy numbers they compiled.

Dawson, Devyn and their 19 yr old brother Daniel (A soccer player at PCC)Were home schooled early on by their mother Lisa, Who challenged them daily to be the best they could be at everything they attempt to do in life.

dan Netz, Their pa, Is an engineer and someone who provided the support needed and in various ways to allow their three children to chase their dreams.

If any of the three Netz teenagers have a game, You might possibly see Dan taking pictures or Lisa in the stands rooting on the Maranatha and PCC teams.

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mister. Netz credits his wife for the diligence she displayed in their early education and their collective drive to seek excellence to this day, And Lisa said her husband analytical nature has been key in all three of their children being able to use their brain while making important decisions as well as being prepared for whatever life might throw their way.

Dawson Netz, A 17 yr old junior, Leads your entire area in wins, deficient ERA and strikeouts, Just for example.

The 6 foot 1 right hander is 6 0 on the mound which has a 0.19 ERA and he already struck out 56 batters in 37 innings frequency.

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during the last two years, Netz is a combined 11 3 with approximately 0.50 ERA and 124 strikeouts in 84 2/3 innings on the hill for Matt Shupper technique.

But completely late in the 2017 season, specially the postseason when Netz really got rolling, And he turned it up intensely throughout this, His frosh year.

Netz moved from a high 80 (mph) Fastball to the low 90 and the on his curveball is said to rival those of MLB pitchers.

He can use any of his pitches at any point in the count, And he has the stones and morale to throw anything from his heat to his splitter or change up in any scenario a game could present him with.

What been key for both Dawson and Devyn is remarkable ability to mix speeds, locals and hitting spots.

Maranatha (11 4 primary, 5 0 in little league) Has arguably the area deepest staff and bench and yet they can be only favored to win an Olympic League championship, Those within the program feel confident they are going to positioned well enough to at least make a run at a CIF SS Division 3 title.

As of thursday, The Minutemen are graded No. 5 causing Arcadia, Temecula area, San Dimas and Chino Hills within that order.

Dawson mind set is literally to never give up a run and when and if this scoreless streak ends, that sometimes it eventually will, He said in a phone employment Tuesday night that he be really (exasperated).

That economical nature for both Dawson and Devyn started at a very young age when they spent hours playing wiffle ball out on the lawn with their older brother Daniel.

Daniel Netz is an outfielder at Pasadena City College for Pat McGee program and someone his younger brother and sister admire for the way he carries himself as a sports athlete and as a person.

They also say Daniel has an cerebral approach to athletics that many do not and they learned from their big brother.

His makes use of on the mound aren all he does for the Minutemen.

He fourth with (hitting) frequent (.312) Among MHS players with nearly 30 at bats, wife or husband fourth in hits (10). His eight RBIs are fifth major.

potential Blessinger (.490 average, 25 bites), Marco Martinez (.412, 14 knocks) as Brock Vradenburg (.333, 13 bites) Have paced the MHS offense over the first 15 games.

Is our ace and has pitched like it solitary time that he on the mound, Maranatha condition Matt Shupper said. He has five walks a little something year. He knows how to pitch instead of just being a thrower. His work ethic and attainments, Along with a high GPA that has Netz sold on the University of Arizona, But simple in June of 2019, Netz might be lured if drafted high enough to begin his specialist career at age 18.

It takes famous brands mentality Dawson has to seek such high ground in everything he does.

Am obsessive about not letting people score, he said. I raise my guidelines, It gives me an advantage, as most players settle for less and I can do that. I want to be the most satisfactory athlete I can be and it also helps me to contribute to my team as much as I can and to the best of my capabilities. Of his high criteria?

Dawson told me that at least for him, along with the talent they have, That it a cute CIF championship or bust, And as difficult as that could be for any program, The Minutemen have a staff and lineup that has the to battle with anyone twice a week.

21. ledna 2020 0:55

JoshuaRaF: Ridden Ukrainian hamlet faces deadly threat

Outside the scenic Ukrainian village of Chugynka, Dozens of men and women in bulletproof vests kneel down and explore every inch of ground.

The faded grass lies within the center of a war zone that has become one of the most mine riddled areas in the world over the past few years.

"a comprehensive village used to use the field" producing hay and grazing cows, asserted Anatoliy Radchenko, A former small business owner who now leads the group of around 30 face masked workers.

"We are developing the skill mine clearing for them, So posting day we can say guys, quite a few, things are all fine here now,

The pine fringed village's former pasture is cordoned off and marked by signs reading "danger, mines" In speech.

"For someone driving a tractor almost always there is the risk of a mine exploding, alleges Andriy, A 32 year old farmer who lives in Chugynka with his and also earns his living from producing grain.

"But it's necessary that you work anyway, the doctor sighs, After telling how a farmer he knows was injured in harvest this year.

Chugynka is exactly 15 miles (25 kilometres) West of the frontline in a war between Ukraine fed government forces and Russian backed separatists.

The conflict has claimed greater 10,000 lives since it broke out in 2014 on a pro Europe uprising in Kiev and Moscow's annexation of the Crimean peninsula.

Russia denies claims it is funnelling troops and arms all over the border to fuel the conflict, Despite engulfing evidence to the contrary.

endure, The UN says more than 1,600 civilians have been killed or wounded by mines this war.

That includes children three of whom died while another was injured in the market in September.

an added two million Ukrainians, and this includes 220,000 offspring, remain at risk.

wild and slow

built with metal detectors, The group near Chugynka search online for mines, Marking the location where they find one with a small flag.

They perfect away report the find to emergency services that can neutralise the threat.

The Ukrainian de mining team was formed in 2016 and is <a href=https://ukrainianwomenonlinedating.blogspot.com/2019/06/2-stereotypes-and-2-truths-about.html>ukraine singles</a> funded by The Swiss backdrop for Mine Action (FSD).

The work is bad and slow

Alexey FILIPPOV, AFP

The work is detrimental and slow, at the same time. near six weeks, The team has covered below what five percent of the 74,000 sq,rectangular metre (18 acre) community.

Two other humanitarian companies, The HALO Trust <a href=https://ukrainianwomen.home.blog/>ukraine chat</a> and Danish Demining Group work in mine clearance in Ukraine. But the trio only work in areas of the country controlled by Kiev.

on the other side of the frontline, In the so called Lugansk and Donetsk People's Republics, The problem is identical.

'Some blame the mother or father's

the manufacturer for Security and Co Operation in Europe estimated in a report last week that 7,000 square kilometres are mined in Eastern Ukraine.

which make it "One of the most densely mined areas ever, The OSCE expresses.

Alexander larg, Then deputy head of the OSCE ceasefire following operation in Ukraine, Told AFP ever before that both sides continued to set mines without marking them.

This runs counter to 2015 peace agreements that have curbed the final violence.

"I think we will suffer for many years, Ivan Prykhodko, The separatist head of the metropolis of Gorlivka in Donetsk, said AFP.

14. ledna 2020 8:51

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13. ledna 2020 2:41

JoshuaRaF: How Russian girls make merry it

Three Kings' Dayis renowned in Russia on January 6 this year. And while New Year's Eve is celebrated by about 90% of Russia's human population, any holiday (jan 7) By about 50% of the citizenry, Three Kings' Day isn't as popular, It's celebrated by only about 10% of Russia's thousands.

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10. ledna 2020 8:48

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10. ledna 2020 5:24

WilliamQuani: Old lady friend gives birth to twins in Calgary

A 60 year old woman produced twins at Calgary's Foothills Hospital Tuesday, members of the family confirmed. She is regarded as the oldest person in Canada to give birth.

children said Ranjit Hayer and her husband have been trying to have a child for years, to no avail. accounts say Hayer, in the first place from India, Returned to the country to receive in vitro fertilization after being turned down in Canada because of her age.

"(Hayer)'s always targeted her nieces and nephews as her own, Said someone you care about who asked not to be identified. "We always prayed so as to have children. It's a very outstanding moment.

"In Indian civilization, children are a blessing. it is really quite, Very uncommon for a husband and wife to not have children,

The oldest known mother to give birth was last year in India when 70 year old Omkari Panwar gave birth to twins after receiving in vitro fertilization.

about 2006, A 67 years old Spanish woman had twins, Her first little children, In spain's capital. That woman also received in vitro fertilization.

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